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Furazidine

  • CAS No.: 1672-88-4
  • Purity: 99%
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Buy Good Quality Furazidine 1672-88-4 with a minimum purity of 99%

  • Molecular Formula: C10H8N4O5
  • Molecular Weight: 264.197
  • Melting Point: 267-270oC (dec.) 
  • Refractive Index: 1.689 
  • PKA: 7.79±0.10(Predicted) 
  • PSA: 120.73000 
  • Density: 1.61 g/cm3 
  • LogP: 1.52850 

Furazidine(Cas 1672-88-4) Usage

Uses and Mechanism of Action

Furagin is used in the management of urinary tract infections caused by susceptible bacteria.
Works by inhibiting bacterial growth and replication, thereby resolving the infection.

Sources

Synthetically manufactured in pharmaceutical laboratories.

Definition

ChEBI: An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [3-(5-nitro-2-furyl)prop-2-en-1-ylidene]amino group (the configuration of the C2C and C2 bonds in the grouping that links the two heterocycles is not specified). A nitrofuran antibiotic with properties similar to nitrofurantoin, furagin is used in the treatment of urinary tract infections.

InChI:InChI=1/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+

1672-88-4 Relevant articles

Synthesis method of 1-((3-(5-nitro-2-furyl)allylidene)amino) hydantoin

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Paragraph 0043; 0045; 0046; 0047; 0050; 0052; 0054, (2018/11/22)

The invention discloses a synthesis meth...

POLYMORPHIC FORMS OF FURAZIDIN

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Page/Page column 5, (2015/12/18)

The invention relates to the crystalline...

1672-88-4 Process route

1-aminohydantoin
6301-02-6

1-aminohydantoin

5-nitrofurylacrolein
52661-56-0,1874-22-2

5-nitrofurylacrolein

1-{[(1E,2E)-3-(5-nitrofuran-2-yl)prop-2-ene-1-ylidene]amino}imidazolidin-2,4-dione
1672-88-4

1-{[(1E,2E)-3-(5-nitrofuran-2-yl)prop-2-ene-1-ylidene]amino}imidazolidin-2,4-dione

Conditions
Conditions Yield
With acetic acid; In water; isopropyl alcohol; for 1h;
97%
1-{[(1E,2E)-3-(5-nitrofuran-2-yl)prop-2-ene-1-ylidene]amino}imidazolidin-2,4-dione
1672-88-4

1-{[(1E,2E)-3-(5-nitrofuran-2-yl)prop-2-ene-1-ylidene]amino}imidazolidin-2,4-dione

Conditions
Conditions Yield
With hydrogenchloride;

1672-88-4 Upstream products

  • 6301-02-6
    6301-02-6

    1-aminohydantoin

  • 1874-22-2
    1874-22-2

    3-(5-nitrofuran-2-yl)-2-propenal

  • 52661-56-0
    52661-56-0

    5-nitrofurylacrolein

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