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Androstan-3-one

  • CAS No.: 1224-95-9
  • Purity: 99%
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1.What is the Androstan-3-one ?

Used in Pharmaceutical Industry:
Androstan-3-one is used as a precursor for the synthesis of various bioactive androgens, which are essential for the development and maintenance of male characteristics and secondary sexual features. It plays a significant role in the treatment of certain medical conditions related to hormonal imbalances.
Used in Perfume Industry:
Androstan-3-one is used as a fragrance ingredient in the perfume industry due to its inherent scent. It contributes to the creation of complex and long-lasting fragrances, enhancing the overall sensory experience of the consumer.
Used in Research Applications:
Androstan-3-one is used as a research compound in the study of neurosteroids and their effects on the central nervous system. It helps in understanding the role of neurosteroids in various physiological processes and their potential therapeutic applications in neurological disorders.

5α-androstan-3β-ol
1224-93-7,7657-50-3,7753-89-1,10085-14-0,15360-52-8,15360-53-9,36216-01-0,36216-02-1,1224-92-6

5α-androstan-3β-ol

androstan-3-one
1224-95-9,118371-41-8

androstan-3-one

Conditions
Conditions Yield
With silica gel; pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 2h;
96%
With Jones reagent; In water; acetone; at 30 ℃; for 2h;
95%
With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 2h;
93%
With pyridinium chlorochromate; In dichloromethane; at 23 ℃; for 16h;
80%
With chromium(VI) oxide; sulfuric acid; In acetone; at 0 ℃; for 0.166667h;
76%
With chromium(VI) oxide; acetic acid; at 4 ℃;
With chromium(VI) oxide;
Epiandrosterone
481-29-8

Epiandrosterone

androstan-3-one
1224-95-9,118371-41-8

androstan-3-one

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 94 percent / hydrazine hydrate, potassium hydroxide / bis-(2-hydroxy-ethyl) ether
2: 76 percent / chromium trioxide, aq. sulfuric acid / acetone / 0.17 h / 0 °C
With chromium(VI) oxide; potassium hydroxide; sulfuric acid; hydrazine hydrate; In acetone; diethylene glycol;
Multi-step reaction with 2 steps
1: sodium methylate; methanol; hydrazine hydrate / 180 °C
2: chromium (VI)-oxide; acetic acid
With chromium(VI) oxide; methanol; sodium methylate; hydrazine hydrate; acetic acid;
Multi-step reaction with 2 steps
1: hydrazine; potassium hydroxide / 1,2-dimethoxyethane / 23 h / Reflux
2: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C
With pyridinium chlorochromate; potassium hydroxide; hydrazine; In 1,2-dimethoxyethane; dichloromethane;

2.What is the CAS number for Androstan-3-one ?

The CAS number of Androstan-3-one is 1224-95-9.

More information of Androstan-3-one 1224-95-9 are:

CAS?Number

1224-95-9

Density

1.014g/cm3

Melting Point

103-104 °C

Boiling Point

368.5°Cat760mmHg

Flash Point

168.7°C

Vapor Pressure

1.27E-05mmHg at 25°C

Refractive Index

1.517

PSA

17.07000

LogP

4.98830

3.What are another words for Androstan-3-one ?

Synonyms?for?Androstan-3-one 1224-95-9:5a-Androstan-3-one (6CI,7CI,8CI);NSC 50893

4.What is the molecular formula of Androstan-3-one?

The chemical formula of ?Androstan-3-one is?C19H30 O which containing 19 Carbon atoms,30 Hydrogen atoms and 1 Oxygen atoms,and the molecular weight of??Androstan-3-one?is 274.447.

5.What is Androstan-3-one (1224-95-9) used for?

Androstan-3-one, also known as Androsterone, is an endogenous steroid hormone, neurosteroid, and pheromone. It is naturally synthesized from the metabolism of testosterone in human beings and animals. Androsterone was the first neurosteroid to be discovered and was subsequently found to be converted into epiandrosterone. It is less active than testosterone but more active than epi-androsterone, and it may exert inhibitory effects on the central nervous system. It is a crucial compound in the biosynthesis of many other bioactive androgens.

InChI:InChI=1/C19H30O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h13,15-17H,3-12H2,1-2H3/t13-,15-,16-,17-,18-,19-/m0/s1

Relevant articles related to Androstan-3-one:

Article

Source

HUMAN GHRELIN O-ACYL TRANSFERASE INHIBITORS

-

Paragraph 0052-0054, (2018/03/09)

Novel and efficient synthesis and antifungal evaluation of 2,3-functionalized cholestane and androstane derivatives

Jursic, Branko S.,Upadhyay, Sunil Kumar,Creech, Clinton C.,Neumann, Donna M.

supporting information; experimental part, p. 7372 - 7375 (2011/02/23)

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